Biomarkers for dementia in Latin American countries: Gaps and opportunities
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2022-09-13Autor(es)
Parra, Mario A.Orellana, Paulina
Leon, Tomas
Cabello, Victoria G.
Henriquez, Fernando
Gomez, Rodrigo
Avalos, Constanza
Damian, Andres
Slachevsky, Andrea
Ibáñez, Agustin
Zetterberg, Henrik
Tijms, Betty M.
Yokoyama, Jennifer S.
Piña-Escudero, Stefanie D.
Cochran, J. Nicholas
Matallana, Diana
Acosta, Daisy
Allegri, Ricardo
Arias-Suárez, Bianca P.
Barra, Bernardo
Behrens, Maria Isabel
Bruck, Sonia M.D.
Busatto, Geraldo
Caramelli, Paulo
Castro-Suarez, Sheila
Contreras, Valeria
Custodio, Nilton
Dansilio, Sergio
De la Cruz-Puebla, Myriam
Cruz de Souza, Leonardo
Diaz, Monica M.
Duque, Lissette
Farías, Gonzalo A.
Ferreira, Sergio T.
Magrath Guimet, Nahuel
Kmaid, Ana
Lira, David
Lopera, Francisco
Mar Meza, Beatriz
Miotto, Eliane C.
Nitrini, Ricardo
Nuñez, Alberto
O’Neill, Santiago
Ochoa, John
Pintado-Caipa, Maritza
França Resende, Elisa de Paula
Risacher, Shannon
Rojas, Luz Angela
Sabaj, Valentina
Schilling, Lucas
Sellek, Allis F.
Sosa, Ana
Takada, Leonel T.
Teixeira, Antonio L.
Unaucho-Pilalumbo, Martha
Duran-Aniotz, Claudia
Autor(es) Corporativo(s)
Pontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimiento
Tipo
Artículo de revista
ISSN
1552-5260 / 1552-5279 (Electrónico)
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Abstract
Limited knowledge on dementia biomarkers in Latin American and Caribbean (LAC) countries remains a serious barrier. Here, we reported a survey to explore the ongoing work, needs, interests, potential barriers, and opportunities for future studies related to biomarkers. The results show that neuroimaging is the most used biomarker (73%), followed by genetic studies (40%), peripheral fluids biomarkers (31%), and cerebrospinal fluid biomarkers (29%). Regarding barriers in LAC, lack of funding appears to undermine the implementation of biomarkers in clinical or research settings, followed by insufficient infrastructure and training. The survey revealed that despite the above barriers, the region holds a great potential to advance dementia biomarkers research. Considering the unique contributions that LAC could make to this growing field, we highlight the urgent need to expand biomarker research. These insights allowed us to propose an action plan that addresses the recommendations for a biomarker framework recently proposed by regional experts.
Cobertura Espacial
América LatinaLink para o recurso
https://alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.12757Fonte
Alzheimer's & Dementia; Volumen 19 Número 2 , Páginas 721 - 735 (2022)
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