Rotavirus vaccines : recent developments and future considerations

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Date
2007Authors
Angel Uribe, JuanitaFranco Cortes, Manuel Antonio
Greenberg, Harry B.
Pontificia Universidad Javeriana. Facultad de Medicina. Instituto de Genética Humana
Type
Artículo de revista
ISSN
740-1526 / 1740-1534 (Electrónico)
Pages
529-539
Item type
Revisión
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Abstract
Two new vaccines have recently been shown to be safe and effective in protecting young children against severe rotavirus gastroenteritis. Although both vaccines are now marketed worldwide, it is likely that improvements to these vaccines and/or the development of future generations of rotavirus vaccines will be desirable. This Review addresses recent advances in our knowledge of rotavirus, the host immune response to rotavirus infection and the efficacy and safety of the new vaccines that will be helpful for improving the existing rotavirus vaccines, or developing new rotavirus vaccines in the future.
Link to the resource
https://www.nature.com/articles/nrmicro1692Source
Nature Reviews Microbiology; Vol. 5 (2007)
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