Análisis de costo-efectividad de las estrategias de tamización de cáncer colorrectal en Colombia

Pinzon Florez, Carlos Eduardo; Roselli, Diego; Gamboa Garay, Oscar Andrés

dc.rights.licence	Atribución-NoComercial 4.0 Internacional	*
dc.contributor.author	Pinzon Florez, Carlos Eduardo
dc.contributor.author	Roselli, Diego
dc.contributor.author	Gamboa Garay, Oscar Andrés
dc.date.accessioned	2020-04-27T17:28:35Z
dc.date.accessioned	2020-05-08T15:26:49Z
dc.date.available	2020-04-27T17:28:35Z
dc.date.available	2020-05-08T15:26:49Z
dc.date.created	2012-10-22
dc.identifier	https://www.valuehealthregionalissues.com/article/S2212-1099(12)00059-3/fulltext	spa
dc.identifier.issn	2212-1099 / 2212-1102 (Electrónico)	spa
dc.identifier.uri	http://hdl.handle.net/10554/48431
dc.format	PDF	spa
dc.format.mimetype	application/pdf	spa
dc.language	spa	spa
dc.rights.uri	http://creativecommons.org/licenses/by-nc/4.0/	*
dc.source	Value in Health Regional Issues; Núm. 1 (2012)	spa
dc.subject	Tamización	spa
dc.subject	Cáncer colorrectal	spa
dc.subject	Costo efectividad	spa
dc.title	Análisis de costo-efectividad de las estrategias de tamización de cáncer colorrectal en Colombia	spa
dc.type	info:eu-repo/semantics/article
dc.type.hasversion	http://purl.org/coar/version/c_ab4af688f83e57aa
dc.description.quartilescopus	Q4	spa
dc.identifier.doi	https://doi.org/10.1016/j.vhri.2012.09.006	spa
dc.description.paginas	190-200	spa
dc.format.soporte	Papel / Electrónico	spa
dc.description.abstractenglish	Objective To evaluate the cost-effectiveness of different screening strategies for colorectal cancer in Colombia. Methods We designed a Markov model to compare the clinical and economic impact in terms of reducing the incidence and mortality from colorectal cancer (CRC). Six screening strategies for adults were compared: fecal occult blood (FOBT) immunochemical and guaiac type, conventional colonoscopy, flexible sigmoidoscopy, and FOBT guaiac and immunochemical type more sigmoidoscopy. We used the third-party payer perspective, including only direct costs, the time horizon was the life expectancy of the Colombian population. We estimated cost-effectiveness ratios (CERs) and incremental cost-effectiveness (ICER). Were performed deterministic sensitivity analysis and probabilistic. We applied a discount rate of 3% in the costs and health outcomes. Results The screening strategy more cost-effective was the FOBT biennial guaiac type. The cost per life year gained was US$10,347.37, US$18,380.64, and US$45,158.05. For FOBT guaiac biennial, FOBT guaiac annual and FOBT inmunoquímica biennial respectively. The ICER is sensitive to the percentage of false positive test for FOBT guaiac type values greater than 10%, and the cost of the test. Conclusions The screening strategy more cost-effective for Colombia is the FOBT biennial guaiac type, using as a threshold the gross domestic product (GDP) per capita in Colombia.	spa
dc.type.local	Artículo de revista	spa
dc.contributor.corporatename	Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Epidemiología Clínica y Bioestadística