Frailty in older adults with mild dementia : dementia with lewy bodies and alzheimer’s disease

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Date
2019-04-09Authors
Borda, Miguel GermánSoennesyn, Hogne
Steves, Claire J.
Vik-Mo, Audun Osland
Pérez-Zepeda, Mario Ulises
Aarsland, Dag
Corporate Author(s)
Pontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimiento
Type
Artículo de revista
ISSN
1664-5464
Pages
176-183
Item type
Artículo de Investigación Original
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Abstract
Introduction: The aim of the study is to describe the frequency of frailty in people with a new
diagnosis of mild dementia due to Alzheimer’s disease (AD) and dementia with Lewy bodies
(DLB). Methods: This is a secondary analysis of the Dementia Study of Western Norway (Demvest). For this study, we analysed a sample of 186 patients, 116 with AD and 70 with DLB. Subjects were included at a time in which mild dementia was diagnosed according to consensus
criteria after comprehensive standardized assessment. Frailty was evaluated retrospectively
using a frailty index generated from existing data. The cut-off value used to classify an older
adult as frail was 0.25. Results: The prevalence of frailty was 25.81% (n = 48). In the DLB group,
37.14% (n = 26) were classified as frail, compared to 18.97% (n = 22) of those with AD (p <
0.001). The adjusted multivariate analysis revealed an OR of 2.45 (1.15–5.23) for being frail in
those with DLB when using AD as the reference group. Conclusion: Frailty was higher than
expected in both types of dementia. The prevalence of frailty was higher in those with DLB
compared to AD. This new finding underscores the need for a multi-systems approach in both
dementias, with a particular focus on DLB
Link to the resource
https://login.ezproxy.javeriana.edu.co/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=edselc&AN=edselc.2-52.0-85064348015&lang=es&site=eds-liveSource
Dementia and Geriatric Cognitive Disorders Extra. Vol. 9 Núm. 1 (2019)
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