Anatomical pathology of the umbilical cord and its maternal and fetal clinical associations in 434 newborns
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Fecha
2018Autor(es)
Olaya Contreras, MercedesGil, Jacky
Salcedo, Juan D.
Salazar Vargas, Ana Janeth
Silva Herrera, Jaime Luis
Bernal, Jaime E.
Autor(es) Corporativo(s)
Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Patología
Tipo
Artículo de revista
ISSN
1093-5266 / 1615-5742 (Electrónico)
Páginas
467-474
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Citación
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Abstract
Introduction: Umbilical cord (UC) abnormalities and their clinical relations in 434 newborns were analyzed. We had
previously reported on clinical associations of long and short UCs with any kind of malformation. This study focuses on
other UC features (insertion, vessels, entanglements, coiling, and knots) and their associations with clinical characteristics
and neonatal prognosis.
Methods: An observational analytic study was performed on placentas from consecutive deliveries. Ordered logistic
regression with bivariate and multivariate analysis was performed to evaluate the relationship between variables of interest
concerning UC abnormalities.
Results: A total of 434 placentas made up the study. UC abnormalities were abnormal insertion, 82 (18.86%); coiling (hypo
and hypercoiled), 177 (40.78%); single umbilical artery (SUA), 4 (0.92%); entanglements, 8 (1.84%); true knots, 3 (0.69%);
webs in UC base, 9 (2.07%); and right twist, 68 (15.67%). After analyzing maternal and fetal complications during pregnancy,
multivariate analysis confirmed the recognized association between malformations and SUA and male gender; further confirmation
was also made between hypertensive disorders of pregnancy and true knots.
Discussion: UC abnormalities associated with undesirable outcomes are varied and should be recognized and described.
Clinical factors associated with anatomical UC abnormalities are not completely understood and justify forthcoming studies.
Enlace al recurso
https://journals.sagepub.com/doi/pdf/10.1177/1093526618758204Fuente
Pediatric and Developmental Pathology; Vol. 21 Núm. 5 (2018)
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