Assessment, Diagnosis, and Treatment of HIV-Associated Neurocognitive Disorder : A Consensus Report of the Mind Exchange Program
Muñoz-Moreno, Jose A.
Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Grupo de Investigación en Enfermedades Infecciosas HUSI - PUJ
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1058-4838 / 1537-6591 (Electrónico)
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Many practical clinical questions regarding the management of human immunodeficiency virus (HIV)–associated neurocognitive disorder (HAND) remain unanswered. We sought to identify and develop practicalanswers to key clinical questions in HAND management. Sixty-six specialists from 30 countries providedinput into the program, which was overseen by a steering committee. Fourteen questions were rated as beingof greatest clinical importance. Answers were drafted by an expert group based on a comprehensive literaturereview. Sixty-three experts convened to determine consensus and level of evidence for the answers. Consensuswas reached on all answers. For instance, good practice suggests that all HIV patients should be screened forHAND early in disease using standardized tools. Follow-up frequency depends on whether HAND is alreadypresent or whether clinical data suggest risk for developing HAND. Worsening neurocognitive impairmentmay trigger consideration of antiretroviral modification when other causes have been excluded. The MindExchange program provides practical guidance in the diagnosis, monitoring, and treatment of HAND.
KeywordsAIDS dementia complex
HIV-associated dementia (HAD)
HIV-associated neurocognitivedisorder (HAND)
Link to the resourcehttps://academic.oup.com/cid/article/56/7/1004/360013
SourceClinical Infectious Diseases; Vol. 56 Núm. 13 (2013)
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