Frequency of tuberculous and non-tuberculous mycobacteria inHIV infected patients from Bogota, Colombia

Murcia-Aranguren, Martha I.; Gómez-Marín, Jorge E.; Alvarado, Fernando S.; Bustillo, José G.; Mendivelson, Ellen de; Gómez, Bertha; León, Clara I.; Triana, William A.; Vargas, Erwing A.; Rodríguez, Edgar

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dc.rights.licence	Atribución-NoComercial 4.0 Internacional	*
dc.contributor.author	Murcia-Aranguren, Martha I.
dc.contributor.author	Gómez-Marín, Jorge E.
dc.contributor.author	Alvarado, Fernando S.
dc.contributor.author	Bustillo, José G.
dc.contributor.author	Mendivelson, Ellen de
dc.contributor.author	Gómez, Bertha
dc.contributor.author	León, Clara I.
dc.contributor.author	Triana, William A.
dc.contributor.author	Vargas, Erwing A.
dc.contributor.author	Rodríguez, Edgar
dc.date.accessioned	2020-09-25T02:52:46Z
dc.date.available	2020-09-25T02:52:46Z
dc.date.created	2001-11-08
dc.identifier	http://www.biomedcentral.com/1471-2334/1/21	spa
dc.identifier.issn	1471-2334	spa
dc.identifier.uri	http://hdl.handle.net/10554/51190
dc.format	PDF	spa
dc.format.mimetype	application/pdf	spa
dc.language	Inglés	spa
dc.rights.uri	http://creativecommons.org/licenses/by-nc/4.0/	*
dc.source	BMC Infectious Diseases; Vol. 1 Núm. 1 (2001)	spa
dc.title	Frequency of tuberculous and non-tuberculous mycobacteria inHIV infected patients from Bogota, Colombia	spa
dc.type	info:eu-repo/semantics/article
dc.type.hasversion	http://purl.org/coar/version/c_ab4af688f83e57aa
dc.description.quartilewos	Q3	spa
dc.description.quartilescopus	Q1	spa
dc.identifier.doi	https://doi.org/10.1186/1471-2334-1-21	spa
dc.description.tipoarticulo	Artículo de investigación	spa
dc.description.paginas	1-21	spa
dc.format.soporte	Papel / Electrónico	spa
dc.description.abstractenglish	Background The prevalence of infections by Mycobacterium tuberculosis and non-tuberculous Mycobacterium species in the HIV-infected patient population in Colombia was uncertain despite some pilot studies. We determined the frequency of isolation of Mycobacterium tuberculosis and of non-tuberculous Mycobacterium species in diverse body fluids of HIV-infected patients in Bogota, Colombia. Methods Patients who attended the three major HIV/AIDS healthcare centres in Bogota were prospectively studied over a six month period. A total of 286 patients were enrolled, 20% of them were hospitalized at some point during the study. Sixty four percent (64%) were classified as stage C, 25% as stage B, and 11% as stage A (CDC staging system, 1993). A total of 1,622 clinical samples (mostly paired samples of blood, sputum, stool, and urine) were processed for acid-fast bacilli (AFB) stain and culture. Results Overall 43 of 1,622 cultures (2.6%) were positive for mycobacteria. Twenty-two sputum samples were positive. Four patients were diagnosed with M. tuberculosis (1.4%). All isolates of M. tuberculosis were sensitive to common anti-tuberculous drugs. M. avium was isolated in thirteen patients (4.5%), but only in three of them the cultures originated from blood. The other isolates were obtained from stool, urine or sputum samples. In three cases, direct AFB smears of blood were positive. Two patients presented simultaneously with M. tuberculosis and M. avium. Conclusions Non-tuberculous Mycobacterium infections are frequent in HIV infected patients in Bogota. The diagnostic sensitivity for infection with tuberculous and non-tuberculous mycobacteria can be increased when diverse body fluids are processed from each patient.	spa
dc.type.local	Artículo de revista	spa
dc.contributor.corporatename	Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Grupo de Investigación en Enfermedades Infecciosas HUSI - PUJ