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dc.rights.licenceAtribución-NoComercial 4.0 Internacional*
dc.contributor.authorOtero, Liliana
dc.contributor.authorRiveros Rivera, Alain
dc.contributor.authorUriza Carrasco, Luis Felipe
dc.contributor.authorMatallana, Diana
dc.contributor.authorHidalgo Martínez, Patricia
dc.contributor.authorReyes, Pablo
dc.date.accessioned2021-02-17T21:02:35Z
dc.date.available2021-02-17T21:02:35Z
dc.date.created2019-05-07
dc.identifierhttps://openres.ersjournals.com/content/5/suppl_3/P119spa
dc.identifier.issn09041850spa
dc.identifier.urihttp://hdl.handle.net/10554/52998
dc.formatPDFspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.titleAssociation of obstructive sleep apnea with cognitive impairment and small vessel diseasespa
dc.type.hasversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.identifier.doihttps://doi.org/10.1183/23120541.sleepandbreathing-2019.P119spa
dc.description.abstractenglishObstructive sleep apnea (OSA) has been associated with mild cognitive impairment (MCI). Cerebral small vessel disease (CSVD) is considered a neuroimaging marker for MCI. Objective: To evaluate the association between OSA, cognitive impairment and vessel disease. Methods: We prospectively recruited individuals diagnosed through polysomnography with severe OSA (S; n=21), moderate OSA (M; n=18), and healthy individuals (H; n=9). Behavioral Data included screening tests with Montreal Cognitive assessment test (MOCA), Ineco Frontal Screening Test (IFS), Language by verbal fluency, Verbal Memory by selective memory verbal test, Attention executive by paced auditory serial addition test (PASAT), selective attention by digit symbol of WAIS, and executive functions like inhibition by Stroop test and Hayling test. Lesions in white matter was established through Magnetic resonance imaging (MRI). Results: The frequency of CSVD was higher in patients with OSA ((H=22%; M=38%; S=38%). Splitting the participants according to SVD, we found significant differences in cognitive parameters such LTMs (nonSVD=29; SVD=38, p=0.05) and PASAT (nonSVD=6.7; SVD=10.6 p=0.03). Data as mean ± SEM. LTMs scores varied according to the group (H=40±6; M=38±3 and S=28±3) with significant differences H vs S (p=0.04) and M vs S (p=0.02). Remaining cognitive measurements, between those groups were not different. Conclusions: These preliminary findings suggest that mild cognitive impairment in patients with OSA is associated with CSVDspa
dc.type.localArtículo de revistaspa
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Enfermedades Crónicas del Adulto
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Neumología
dc.identifier.instnameinstname:Pontificia Universidad Javerianaspa
dc.identifier.reponamereponame:Repositorio Institucional - Pontificia Universidad Javerianaspa
dc.identifier.repourlrepourl:https://repository.javeriana.edu.cospa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.description.orcidhttps://orcid.org/0000-0002-1923-3934spa
dc.description.orcidhttps://orcid.org/0000-0001-6529-7077spa
dc.description.orcidhttps://orcid.org/0000-0001-5576-9341spa
dc.description.googlescholarhttps://scholar.google.com/citations?hl=es&user=mvM0fxQAAAAJspa
dc.description.googlescholarhttps://scholar.google.com/citations?user=Z9KzTnoAAAAJ&hl=es&oi=aospa
dc.description.googlescholarhttps://scholar.google.com/citations?user=SWsgTD8AAAAJ&hl=es&oi=aospa
dc.description.googlescholarhttps://scholar.google.com/citations?user=kaGongoAAAAJ&hl=es&oi=aospa
dc.description.googlescholarhttps://scholar.google.com/citations?user=MpWOE1oAAAAJ&hl=es&oi=aospa
dc.relation.citationstartpage119spa
dc.relation.citationendpage119spa
dc.relation.ispartofjournalEuropean Respiratory Journal, Supplementspa
dc.relation.citationvolume5spa
dc.relation.citationissue3spa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa


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Atribución-NoComercial 4.0 Internacional
Except where otherwise noted, this item's license is described as Atribución-NoComercial 4.0 Internacional