Risk factors and fetal outcomes for preeclampsia in a Colombian cohort
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Fecha
2020-09Autor(es)
Ayala-Ramírez, PaolaSerrrano, Natalia
Barrera, Viviana
Bejarano, Juan Pablo
Silva, Jaime Luis
Martínez, Rodolfo
Gil, Fabian
Olaya-C, Mercedes
García-Robles, Reggie
Autor(es) Corporativo(s)
Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Epidemiología Clínica y Bioestadística
Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Patología
Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Ginecología y Obstetricia
Tipo
Artículo de revista
ISSN
2405-8440
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Título en inglés
Risk factors and fetal outcomes for preeclampsia in a Colombian cohortAbstract
In Latin America and the Caribbean, hypertensive pregnancy disorders are responsible for almost 26% of allmaternal deaths [1] and, in Colombia, they account for 59% of all severe maternal morbidity (SMM) cases, and59.7% of all SMM cases in adolescents [2]. One of the most important hypertensive pregnancy disorders ispreeclampsia (PE). Lives can be saved, if PE is prevented, or detected early and properly managed. Prevention anddetection depend on identifying the risk factors associated with PE, and, as these have been shown vary bypopulation, they should be determined on a population-by-population basis. The following study utilized thenested case-control model to evaluate 45 potential PE risk factors of a cohort in Bogot a, Colombia, making itperhaps the most comprehensive study of its kind in Colombia. It found PE to have a statistically significantassociation with 7 of the 45 factors evaluated: 1) pre-gestational BMI>30 kg/m2, 2) pregnancy weight gain>12kg, 3) previous history preeclampsia/eclampsia, 4) previous history of IUGR-SGA (Intrauterine GrowthRestriction-Small for Gestational Age), 5) maternal age<20 or 35 years (20–34 was not associated), and 6)family history of diabetes. Finally, prenatal consumption of folic acid was found to lower the risk of PE. Werecommend that, in Colombia, factors 1–6 be used to identify at risk mothers during pregnancy check-ups; thatmothers be encouraged to take folic acid during pregnancy; and, that Colombia's health system and public policyaddress the problem of pregestational obesity.
Keywords
Public healthObstetrics
Pregnancy
Reproductive system
Pediatrics
Pregnancy complications
Reproductive health
Hypertension
Pregnancy outcomes
Cobertura espacial
ColombiaFuente
Heliyon; Volumen 6 Número 9 , Páginas 1 - 12 (2020)
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