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dc.rights.licenceAttribution-NonCommercial 4.0 International*
dc.contributor.authorChaves Santiago, Walter Gabriel
dc.contributor.authorDiaztagle Fernández, Juan José
dc.contributor.authorSprockel, John
dc.contributor.authorHernández Cruz, José Ignacio
dc.contributor.authorBenavides Bermúdez, Javier Mauricio
dc.contributor.authorHenao Carrillo, Diana Cristina
dc.contributor.authorMejía López, María Gimena
dc.contributor.authorVargas Buitrago, Viviana
dc.contributor.authorCarrero Rojas, Nubia Esperanza
dc.contributor.authorFuentes Restrepo, Carmelo Rafael
dc.contributor.authorAlba Saavedra, Magda Janeth
dc.contributor.authorCarvajal Flechas, Ricardo Andrés
dc.contributor.authorContento Anaya, Fabio Andrés
dc.date.accessioned2021-04-13T02:17:05Z
dc.date.available2021-04-13T02:17:05Z
dc.date.created2014-11-06
dc.identifierhttp://www.scielo.org.co/scielo.php?script=sci_abstract&pid=S0120-24482014000400003&lng=en&nrm=iso&tlng=enspa
dc.identifier.issn0120-2448spa
dc.identifier.urihttp://hdl.handle.net/10554/53511
dc.description.abstractIntroducción: la falla cardiaca (FC) es una de las principales causas de morbimortalidad a nivel mundial, la cual ha experimentado aumento gradual de su incidencia sin variación importante en su desenlace en las dos últimas décadas. En Colombia muy pocos estudios evalúan factores asociados a mortalidad por falla cardiaca. Métodos: estudio de cohorte prospectivo en el que se incluyeron pacientes con diagnóstico de falla cardiaca descompensada al momento del ingreso a urgencias, entre febrero de 2010 y marzo de 2013. Se calculó el tamaño de muestra y se realizó un análisis multivariado para la evaluación de los factores de riesgo asociados a mortalidad intrahospitalaria y a 30 días. Resultados: se incluyeron 462 pacientes. La mortalidad hospitalaria fue de 8.9% y a 30 días de 13.8%, en el modelo multivariado para el desenlace mortalidad intrahospitalaria se observó que la única variable con significancia estadística fue el BUN ≥43 mg/dL (OR, 3.45 [IC 95% 1.54-7.74], p= 0.003). Para la mortalidad a 30 días, la estancia hospitalaria >5 días (OR, 2.23 [IC 95% 1.20-4.12], p= 0.011), el BUN ≥43 mg/dL (OR, 2.55 [IC 95% 1.31-4.94], p= 0.005) y el NT-proBNP ≥ 4630 pg/dL (OR, 2.47 [IC 95% 1.30-4.70], p= 0.006). Conclusiones: la mortalidad intrahospitalaria de los pacientes con falla cardiaca descompensada en la población evaluada fue alta. En los análisis multivariados, se encontró que el BUN ≥ 43 mg/dL fue el único factor de riesgo independiente asociado a mortalidad intrahospitalaria; mientras que la mortalidad a 30 días se relacionó además con el NT-proBNP y la estancia hospitalaria superior a cinco días.spa
dc.formatPDFspa
dc.format.mimetypeapplication/pdfspa
dc.language.isospaspa
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectFalla cardiacaspa
dc.subjectMortalidadspa
dc.subjectFactores de riesgospa
dc.subjectNT-ProBNPspa
dc.titleFactores asociados a mortalidad en pacientes con falla cardiaca descompensadaspa
dc.type.hasversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.title.englishFactors associated with mortality in patients with decompensated heart failurespa
dc.subject.keywordHeart failurespa
dc.subject.keywordMortalityspa
dc.subject.keywordRisk factorsspa
dc.subject.keywordNT-proBNPspa
dc.description.abstractenglishIntroduction: heart failure is one of the main causes of morbidity and mortality worldwide; it has experienced a gradual increase in incidence with no significant variation in outcome in the last two decades. In Colombia there are no studies to evaluate risk factors for mortality, which is the subject of this study. Methods: prospective cohort study in which patients with diagnosis of decompensated heart failure on admission to the emergency department between February 2010 and March 2013 were included. The sample size was calculated and a multivariate analysis was performed to evaluate the risk factors associated with in-hospital and 30-day mortality. Results: 462 patients were included. Hospital mortality was 8.9% and 30-day mortality 13.8%; in the multivariate model for hospital mortality outcome was observed that the only variable with statistic significance was BUN ≥ 43 mg/dL (OR, 3.45 [95% CI 1.54- 7.74], p = 0.003). For 30 day mortality, hospital stay > 5 days (OR, 2.23 [95% CI 1.20-4.12], p = 0.011), BUN ≥43 mg/dL (OR, 2.55 [95% CI 1.31-4.94] , p = 0.005) and NT-proBNP ≥ 4630 pg/dL (OR, 2.47 [95% CI 1.30-4.70], p = 0.006). Conclusions: in-hospital mortality in patients with decompensated heart failure in the study population was high. In multivariate analysis, it was found that BUN ≥ 43 mg/dL was the only independent risk factor associated with hospital mortality, while the 30-day mortality was also associated with NT-proBNP and hospital stay greater than five days.spa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.type.localArtículosspa
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Departamento de Endocrinología
dc.identifier.instnameinstname:Pontificia Universidad Javerianaspa
dc.identifier.reponamereponame:Repositorio Institucional - Pontificia Universidad Javerianaspa
dc.identifier.repourlrepourl:https://repository.javeriana.edu.cospa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.description.orcidhttps://orcid.org/0000-0002-7021-6769spa
dc.relation.citationstartpage314spa
dc.relation.citationendpage320spa
dc.relation.ispartofjournalActa Medica Colombianaspa
dc.description.indexingN/Aspa
dc.relation.citationvolume39spa
dc.relation.citationissue4spa


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