Thyroid stimulating hormone levels and geriatric syndromes : secondary nested case–control study of the Mexican Health and Aging Study
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Date
2021-10-02Authors
Perez Zepeda, Mario UlisesAlmeda Valdes, Paloma
Fernandez Villa, Julio Manuel
Gomez Arteaga, Ronald Camilo
Borda, MG.
Cesari, Matteo
Corporate Author(s)
Pontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimiento
Type
Artículo de revista
ISSN
1878-7649 / 1878-7657 (Electrónico)
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Abstract
Purpose: To determine the incidence of geriatric syndromes (GS) in community dwelling older adults with subclinical
hypothyroidism.
Methods: This is an analysis from the Mexican Health and Aging Study, of a subsample of 2089 subjects with TSH determination. From this last subsample, we included 1628 individuals with TSH levels in the subclinical range (4.5–10 µU/ml).
Results: The multivariate analysis showed that when comparing data obtained from the 2012 wave with the 2015 wave
results, there was a signifcant incidence of some GS such as falls (OR 1.79, CI 1.16–2.77, p=0.0116), fatigue (OR 2.17, CI
1.40–3.38, p=0.0348) and depression (OR 1.70, CI 1.06–2.71, p=0.0246) among the subclinical hypothyroidism group.
Conclusion: This study showed a greater incidence of GS in subjects 50 years and older with sub-clinical hypothyroidism,
when compared to those with normal thyroid function.
Keywords
Hormona estimulante del tiroidesEnvejecimiento
Síndromes geriátricos
Enfermedad crónica
Hipotiroidismo subclínico
Keywords
Thyroid stimulating hormoneAging
Geriatric syndromes
Chronic disease
Subclinical hypothyroidism
Spatial coverage
MéxicoCommunity
Pacientes con síndromes geriátricosLink to the resource
https://link.springer.com/article/10.1007%2Fs41999-021-00564-7Source
European Geriatric Medicine; Volumen 13 , Páginas 139 - 145 (2021)
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