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How does per-oral endoscopic myotomy compare to Heller myotomy? The Latin American perspective

dc.rights.licenceAtribución-NoComercial 4.0 Internacional*
dc.contributor.authorKahaleh, Michel
dc.contributor.authorTyberg, Amy
dc.contributor.authorSuresh, Supriya
dc.contributor.authorLambroza, Arnon
dc.contributor.authorGaidhane, Monica
dc.contributor.authorZamarripa, Felipe
dc.contributor.authorMartínez, Guadalupe Ma
dc.contributor.authorCarames, Juan C
dc.contributor.authorMoura, Eduardo T
dc.contributor.authorFarias, Galileu F
dc.contributor.authorPorfilio, Maria G
dc.contributor.authorNieto, Jose
dc.contributor.authorRey, Mario
dc.contributor.authorRodriguez Casas, Fernando
dc.contributor.authorMondragón Hernández, Oscar V
dc.contributor.authorVargas, Romulo Dario
dc.contributor.authorCañadas, Raúl
dc.contributor.authorHani, Albis
dc.contributor.authorMuñoz, Guillermo
dc.contributor.authorCastillo, Bismarck
dc.contributor.authorLukashok, Hannah P
dc.contributor.authorRobles-Medranda, Carlos
dc.contributor.authorde Moura, Eduardo G
dc.coverage.spatialAmérica Latinaspa
dc.date.accessioned2022-05-04T13:13:27Z
dc.date.available2022-05-04T13:13:27Z
dc.date.created2020-09-22
dc.identifierhttps://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1223-1521spa
dc.identifier.issn2364-3722 / 2196-9736 (Electrónico)spa
dc.identifier.urihttp://hdl.handle.net/10554/59731
dc.formatPDFspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.titleHow does per-oral endoscopic myotomy compare to Heller myotomy? The Latin American perspectivespa
dc.type.hasversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.description.quartilescopusQ4spa
dc.identifier.doihttps://doi.org/10.1055/a-1223-1521spa
dc.description.abstractenglishBackground and study aims Both Heller myotomy (HM) and per-oral endoscopic myotomy (POEM) are efficacious therapies for achalasia. The efficacy and safety of POEM vs HM in Latin America and specifically in patients with Chagas disease is unknown. Patients and methods Consecutive patients undergoing either HM or POEM for achalasia were included from nine Latin American centers in a prospective registry over 5 years. Technical success was defined as undergoing a successful myotomy. Clinical success was defined as achieving an Eckardt score < 3. Data on demographics, procedure info, Eckardt score, and adverse events (AEs) were collected. Student’s t test, Chi squared, and logistic regression analyses were conducted. Results One hundred thirty-three patients were included (59 male; 44 %; mean age 47). POEM was performed in 69 patients, HM in 64 patients. A total of 35 patients had Chagas disease, 17 of 69 in the POEM group, 18 of 64 in the HM group. Both groups had significant reduction in Eckardt scores (P < 0.00001), but successful initial therapy was significantly higher in the POEM group compared to the HM group (P = 0.01304). AEs were similar in both group (17 % vs 14%) and consisted of pneumothorax (n = 3 vs 2), bleeding requiring transfusion (n = 3 vs 2), and mediastinitis (n = 3 vs 1). Hospital stay was longer in the HM group than in the POEM group (P < 0.00001). In the Chagas subgroup, postprocedure Eckardt score in the POEM group was significantly reduced by 5.71 points (P < 0.00001) versus 1.56 points in the HM group (P = 0.042793). Conclusion Both HM and POEM are efficacious for achalasia, but POEM was associated with higher initial therapy success and shorter hospital stay in Latin America. In Chagas patients with achalasia, POEM was significantly more effective than HM.spa
dc.type.localArtículo de revistaspa
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Gastroenterologíaspa
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Hospital Universitario San Ignaciospa
dc.identifier.instnameinstname:Pontificia Universidad Javerianaspa
dc.identifier.reponamereponame:Repositorio Institucional - Pontificia Universidad Javerianaspa
dc.identifier.repourlrepourl:https://repository.javeriana.edu.cospa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.description.orcidhttps://orcid.org/0000-0001-5660-6229spa
dc.description.orcidhttps://orcid.org/0000-0003-2938-7731spa
dc.description.orcidhttps://orcid.org/0000-0002-9219-4548spa
dc.relation.citationstartpageE1392spa
dc.relation.citationendpageE1397spa
dc.relation.ispartofjournalEndoscopy International Openspa
dc.contributor.javerianateacherVargas Rubio, Romulo Dario
dc.contributor.javerianateacherCañadas Garrido, Raul Antonio
dc.contributor.ascribedclinicalteacherHani Amador, Albis Cecilia
dc.description.indexingRevista Internacional - Indexadaspa
dc.relation.citationvolume8spa
dc.relation.citationissue10spa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa


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