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Antifungal prophylaxis following heart transplantation : systematic review

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dc.contributor.authorUribe, Luis G.
dc.contributor.authorCortés, Jorge A.
dc.contributor.authorMontoya, José G.
dc.contributor.authorGranados, Carlos E.
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Departamento de Radiología e Imágenes Diagnósticas
dc.date.accessioned2020-10-27T21:39:15Z
dc.date.available2020-10-27T21:39:15Z
dc.date.created2014-01-30
dc.description.abstractenglishPatients with heart transplantation have a high incidence of infectious complications, especially fungal infections. The aim of the systematic review was to determine the best pharmacological strategy to prevent fungal infections among patients with heart transplant. We searched the PubMed and Embase databases for studies reporting the effectivenesss of pharmacologic strategies to prevent fungal infections in adult patient with a heart transplant. Our search yielded five studies (1176 patients), four of them with historical controls. Two studies used inhaled amphotericin B deoxycholate, three used itraconazole and one used targeted echinocandin. All studies showed significant reduction in the prophylaxis arm. Different products, doses and outcomes were noted. There is a highly probable benefit of prophylaxis use, however, better studies with standardised doses and comparators should be performed.spa
dc.description.paginas429-436spa
dc.description.quartilescopusQ1spa
dc.description.quartilewosQ1spa
dc.description.tipoarticuloArtículo originalspa
dc.formatPDFspa
dc.format.mimetypeapplication/pdfspa
dc.format.soportePapel / Electrónicospa
dc.identifierhttps://onlinelibrary.wiley.com/doi/epdf/10.1111/myc.12179spa
dc.identifier.doihttps://doi.org/10.1111/myc.12179spa
dc.identifier.issn0933-7407 / 1439-0507 (Electrónico)spa
dc.identifier.urihttp://hdl.handle.net/10554/51538
dc.languageInglésspa
dc.rights.licenceAtribución-NoComercial 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.sourceMycoses; Vol. 57 (2014)spa
dc.subject.keywordAntifungal agentsspa
dc.subject.keywordAntifungal agents/therapeutic usespa
dc.subject.keywordAspergillusspa
dc.subject.keywordHeart trasplantationspa
dc.subject.keywordHeart transplantationspa
dc.titleAntifungal prophylaxis following heart transplantation : systematic reviewspa
dc.typeinfo:eu-repo/semantics/article
dc.type.hasversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.localArtículo de revistaspa

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