Logotipo del repositorio
 

Tongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodies

Vista sencilla de ítem
dc.contributor.ascribedclinicalteacherBorda, Miguel Germán
dc.contributor.authorBorda, Miguel Germán
dc.contributor.authorCastellanos-Perilla, Nicolás
dc.contributor.authorTovar Rios, Diego Alejandro
dc.contributor.authorFerreira, Daniel
dc.contributor.authorDuque, Gustavo
dc.contributor.authorAarsland, Dag
dc.contributor.bachelorstudentCastellanos-Perilla, Nicolás
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimientospa
dc.coverage.spatialNoruega
dc.date.accessioned2022-02-08T17:53:36Z
dc.date.available2022-02-08T17:53:36Z
dc.date.created2022-02-01
dc.description.abstractenglishBackground: Age-related neurodegeneration, sarcopenia, and ectopic fat accumulation are conditions with shared pathways that remain poorly understood. We have measured muscle volume and fat accumulation in masseter and tongue muscle, and aim to explore their association with the total grey matter volume using MRI in older adults recently diagnosed with Alzheimer's disease (AD) and Dementia with Lewy bodies (DLB). Methods: In this cross-sectional study, people newly diagnosed with mild AD (n=33) and DLB (n=20) underwent structural head MRI. Muscle volume and intramuscular fat (iMAT) of the tongue and masseter were computed using Slice-O-Matic software for segmentation. Total grey volume and hippocampal volumetric segmentation were performed with the FreeSurfer image analysis suite version 6.0. Independent regression models were employed to analyse the associations. Results: Tongue iMAT was higher and total grey volume lower in DLB compared to AD. In the DLB group, tongue muscle was positively associated with total grey matter volume Est 0.92 (SE 0.24 p-value 0.002), left- Est 0.01 (SE 0.0028 p-value 0,002), and right- Est 0.0088 (SE 0.0027 p-value: 0.005) hippocampal volume. There were no statistically significant results for AD. Conclusion: Tongue muscle volume was positively associated with hippocampal and total grey volume in DLB. Longitudinal designs are required to explore the extent and significance of this association.spa
dc.description.comunidadPacientes con Enfermedad de Alzheimer
dc.description.comunidadPacientes con Demencia con cuerpos de Lewy
dc.description.cvlachttps://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001429659&lang=esspa
dc.description.googlescholarhttps://scholar.google.com/citations?user=MrICwaMAAAAJ&hl=enspa
dc.description.indexingRevista Internacional - Indexadaspa
dc.description.orcidhttps://orcid.org/0000-0001-5832-0603spa
dc.description.orcidhttps://orcid.org/0000-0002-8229-2611
dc.description.publindexA1
dc.description.quartilescopusQ1spa
dc.description.quartilewosQ2spa
dc.formatPDFspa
dc.format.mimetypeapplication/pdfspa
dc.identifierhttps://www.sciencedirect.com/science/article/pii/S0167494322000280?via%3Dihubspa
dc.identifier.doihttps://doi.org/10.1016/j.archger.2022.104647spa
dc.identifier.instnameinstname:Pontificia Universidad Javerianaspa
dc.identifier.issn0167-4943 / 1872-6976 (Electrónico)spa
dc.identifier.reponamereponame:Repositorio Institucional - Pontificia Universidad Javerianaspa
dc.identifier.repourlrepourl:https://repository.javeriana.edu.cospa
dc.identifier.urihttp://hdl.handle.net/10554/59016
dc.language.isoengspa
dc.relation.citationendpage6spa
dc.relation.citationstartpage1spa
dc.relation.citationvolume100spa
dc.relation.ispartofjournalArchives of Gerontology and Geriatricsspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.licenceAtribución-NoComercial 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectDemenciaspa
dc.subjectGrasa intramuscularspa
dc.subjectMúsculospa
dc.subjectDemencia con cuerpos de Lewyspa
dc.subjectEnfermedad de Alzheimerspa
dc.subjectSarcopeniaspa
dc.subject.keywordDementiaspa
dc.subject.keywordIntramuscular fatspa
dc.subject.keywordMusclespa
dc.subject.keywordDementia with Lewy Bodiesspa
dc.subject.keywordAlzheimer's diseasespa
dc.subject.keywordSarcopeniaspa
dc.titleTongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodiesspa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.type.hasversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.localArtículo de revistaspa

Archivos

Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
Tongue muscle mass is associated.pdf
Tamaño:
2.2 MB
Formato:
Adobe Portable Document Format
Descripción:
Artículo
Descargar
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
2.54 KB
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar

Colecciones

Artículos