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Risk factors associated with methicillin-resistant Staphylococcus aureus skin and soft tissue infections in hospitalized patients in Colombia

dc.contributor.authorValderrama-Beltrán, Sandra
dc.contributor.authorGualtero, Sandra
dc.contributor.authorÁlvarez-Moreno, Carlos
dc.contributor.authorGil, Jacky
dc.contributor.authorRuiz J, Alvaro
dc.contributor.authorRodríguez, José Yesid
dc.contributor.authorOsorio, Johanna
dc.contributor.authorTenorio, Ivan
dc.contributor.authorGómez Quintero, Carlos
dc.contributor.authorMackenzie, Sebastián
dc.contributor.authorCaro, María Alejandra
dc.contributor.authorZhong, Alberto
dc.contributor.authorArias, Gerson
dc.contributor.authorBerrio, Indira
dc.contributor.authorMartinez, Ernesto
dc.contributor.authorCortés, Gloria
dc.contributor.authorDe la Hoz, Alejandro
dc.contributor.authorArias, Cesar A.
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Departamento de Epidemiología Clínica y Bioestadística
dc.coverage.spatialAmérica del Surspa
dc.coverage.spatialColombiaspa
dc.date.accessioned2020-03-19T12:13:26Z
dc.date.accessioned2020-04-15T13:25:16Z
dc.date.available2020-03-19T12:13:26Z
dc.date.available2020-04-15T13:25:16Z
dc.date.created2019-07-19
dc.description.abstractenglishObjectives: Methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections (SSTIs) represent a major clinical problem in Colombia. The aim of this study was to evaluate the risk factors associated with MRSA SSTI in Colombia. Methods: A multicenter cohort study with nested case–control design was performed. Patients with an SSTI with at least 48 h of inpatient care were included. Patients with an MRSA SSTI were considered the case group and patients with either a non-MRSA SSTI or with an Methicillin-susceptible S. aureus (MSSA) SSTI were the control groups. A multivariate logistic regression approach was used to evaluate risk factors associated with MRSA SSTI with two different statistical models. Results: A total 1134 patients were included. Cultures were positive for 498 patients, of which 52% (n = 259) were Staphylococcus aureus. MRSA was confirmed in 68.3% of the S. aureus cultures. In the first model, independent risk factors for MRSA SSTI were identified as the presence of abscess (P<0.0001), cellulitis (P = 0.0007), age 18–44 years (P = 0.001), and previous outpatient treatment in the previous index visit (P = 0.003); surgical site infection was a protective factor (P = 0.008). In the second model, the main risk factor found was previous outpatient treatment in the previous index visit (P = 0.013). Conclusions: Community-acquired SSTIs in Colombia are commonly caused by MRSA. Therefore, clinicians should consider MRSA when designing the initial empirical treatment for purulent SSTI in Colombia, although there seems to be low awareness of this fact.spa
dc.description.comunidadPacientes hospitalizadosspa
dc.description.paginas60-66spa
dc.description.quartilescopusQ1spa
dc.description.quartilewosQ2spa
dc.formatPDFspa
dc.format.mimetypeapplication/pdfspa
dc.format.soportePapel / Electrónicospa
dc.identifierhttps://www.ijidonline.com/article/S1201-9712(19)30292-9/fulltext#%20spa
dc.identifier.doihttps://doi.org/10.1016/j.ijid.2019.07.007spa
dc.identifier.issn12019712 / 18783511 (Electrónico)spa
dc.identifier.urihttp://hdl.handle.net/10554/47723
dc.languagespaspa
dc.rights.licenceAtribución-NoComercial 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.sourceInternational Journal of Infectious Diseases; Vol. 87 (2019)spa
dc.subject.keywordStaphylococcal skin infectionsspa
dc.subject.keywordMethicillin-resistantspa
dc.subject.keywordStaphylococcus aureusspa
dc.subject.keywordRisk factorsspa
dc.subject.keywordAbscessspa
dc.titleRisk factors associated with methicillin-resistant Staphylococcus aureus skin and soft tissue infections in hospitalized patients in Colombiaspa
dc.typeinfo:eu-repo/semantics/article
dc.type.hasversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.localArtículo de revistaspa

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