Genetic population analysis of 17 Y-chromosomal STRs in three states (Valle del Cauca, Cauca and Narino) from Southwestern Colombia
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2009-01-17Autor(es) Corporativo(s)
Pontificia Universidad Javeriana. Facultad de Medicina. Instituto de Genética Humana
Tipo
Artículo de revista
ISSN
1752-928X / 1878-7487 (Electrónico)
Páginas
204-211
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Abstract
Seventeen Y-chromosomal (DYS19, DYS389 1/11, DYS390, DYS391, DYS392, DYS393, DYS438, DYS439, DYS437, DYS448, DYS456, DYS458, DYS635, YGATA-H4 and DYS385a/b) short tandem repeat (STR) polymorphic systems were typed in three South West Colombian populations: Valle (short term for Valle del Cauca), Cauca and Nariño. DYS385a/b showed the highest gene diversity in the three populations. A total of 287 different Y-chromosome haplotypes were observed in the 308 males analyzed, and the haplotype diversity among populations was 0.9977. The most frequent haplotype was observed only three times and only nineteen others were observed two times. The highest gene diversity was found in Valle and the lowest in Cauca. Analysis of molecular variance (AMOVA) revealed that variation is mainly within populations (99.1%) in agreement with previous results in European populations. In conclusion, these populations could be pooled together in order to create one “Colombian-Mestizo” database for forensic use.
Keywords
Forensic scienceY-Chromosome
DNA typing
STR
Haplotype
DYS19
DYS385a
DYS385b
DYS389I
DYS389II
DYS390
DYS391
DYS392
DYS393
DYS438
DYS439
DYS437
DYS448
DYS456
DYS458
DYS635
GATA-H4
Colombia
Population genetics
Cobertura Espacial
ColombiaLink para o recurso
https://www-clinicalkey-es.ezproxy.javeriana.edu.co/#!/content/journal/1-s2.0-S1752928X08002333Fonte
Journal of Forensic and Legal Medicine; Vol. 16 Núm. 4 (2009)
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