Impact of sensor-augmented pump therapy with predictive low-glucose management on hypoglycemia and glycemic control in patients with type 1 diabetes mellitus : 1-year follow-up
dc.contributor.author | Gómez, Ana María | |
dc.contributor.author | Henao, Diana C. | |
dc.contributor.author | Leguizamón, Guillermo | |
dc.contributor.author | Rondón, Martín A. | |
dc.contributor.author | Muñoz, Oscar | |
dc.contributor.author | García Jaramillo, María A. | |
dc.contributor.author | León Vargas, Fabián | |
dc.contributor.author | Taboada, Lucía B. | |
dc.contributor.corporatename | Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Epidemiología Clínica y Bioestadística | |
dc.date.accessioned | 2020-05-08T12:02:22Z | |
dc.date.available | 2020-05-08T12:02:22Z | |
dc.date.created | 2019-07-10 | |
dc.description.abstractenglish | AIMS: To describe real-life experience with sensor-augmented pump therapy with predictive low-glucose management (SAPT-PLGM), in terms of hypoglycemia and glycemic control after one year of follow-up in T1D patients with hypoglycemia as the main indication of therapy. METHODS: Retrospective cohort study under real life conditions. Baseline and one-year follow-up variables of glycemic control, hypoglycemia and glycemic variability were compared. RESULTS: Fifty patients were included, 31 on prior treatment with SAPT with low-glucose suspend (LGS) feature and 19 on multiple dose insulin injections (MDI). Mean HbA1c decreased in the MDI group (8.24%-7.08%; p = 0.0001). HbA1c change was not significant in the SAPT-LGS group. Area under the curve (AUC) below 70 mg/dl improved in both SAPT-LGS and MDI groups while AUC, %time and events below 54 mg/dl decreased in SAPT-LGS group. Glycemic variability improved in the MDI group. Less patients presented severe hypoglycemia with SAPT-PLGM in both groups, however the change was non-significant. CONCLUSIONS: Under real life conditions, SAPT-PLGM reduced metrics of hypoglycemia in patients previously treaded with MDI and SAPT-LGS without deteriorating glycemic control in SAPT-LGS patients, while improving it in patients treated with MDI. | spa |
dc.description.paginas | 2625-2631 | spa |
dc.description.quartilescopus | Q2 | spa |
dc.description.tipoarticulo | Artículo original | spa |
dc.format | spa | |
dc.format.mimetype | application/pdf | spa |
dc.format.soporte | Papel / Electrónico | spa |
dc.identifier | https://eds-a-ebscohost-com.ezproxy.javeriana.edu.co/eds/detail/detail?vid=1&sid=3eb45100-1e58-438f-83f2-c9564389522e%40sessionmgr4007&bdata=Jmxhbmc9ZXMmc2l0ZT1lZHMtbGl2ZQ%3d%3d#AN=edselc.2-52.0-85068894227&db=edselc | spa |
dc.identifier.doi | https://doi.org/10.1016/j.dsx.2019.07.024 | spa |
dc.identifier.issn | 18780334 / 18714021 (Electrónico) | spa |
dc.identifier.uri | http://hdl.handle.net/10554/49109 | |
dc.rights.licence | Atribución-NoComercial 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.source | Diabetes and Metabolic Syndrome: Clinical Research and Reviews; Vol. 13 Núm. 4 (2019) | spa |
dc.subject.keyword | Diabetes mellitus | spa |
dc.subject.keyword | Glycated hemoglobin A | spa |
dc.subject.keyword | Hypoglycemia | spa |
dc.subject.keyword | Insulin infusion systems | spa |
dc.subject.keyword | Sensor-augmented pump therapy | spa |
dc.subject.keyword | Type 1 | spa |
dc.title | Impact of sensor-augmented pump therapy with predictive low-glucose management on hypoglycemia and glycemic control in patients with type 1 diabetes mellitus : 1-year follow-up | spa |
dc.type | info:eu-repo/semantics/article | |
dc.type.hasversion | http://purl.org/coar/version/c_ab4af688f83e57aa | |
dc.type.local | Artículo de revista | spa |
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