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Risk factors associated with acute kidney injury in a cohort of hospitalized patients with COVID-19

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dc.contributor.authorContreras, Kateir
dc.contributor.authorBarbosa, Oscar
dc.contributor.authorMunoz, Ana Cecilia
dc.contributor.authorSuárez, Juan Sebastián
dc.contributor.authorGonzalez Gonzalez, Camilo Alberto
dc.contributor.authorVargas, Diana Carolina
dc.contributor.authorRodriguez Sanchez, Martha Patricia
dc.contributor.authorGarcía Padilla, Paola Karina
dc.contributor.authorValderrama Rios, Martha Carolina
dc.contributor.authorCortés, Jorge Alberto
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Nefrologíaspa
dc.contributor.javerianateacherContreras, Kateir
dc.contributor.javerianateacherGonzalez Gonzalez, Camilo Alberto
dc.contributor.javerianateacherRodriguez Sanchez, Martha Patricia
dc.contributor.javerianateacherGarcía Padilla, Paola Karina
dc.coverage.cityBogotá (Colombia)spa
dc.coverage.spatialColombiaspa
dc.coverage.temporal2020-2021spa
dc.date.accessioned2023-08-28T16:53:18Z
dc.date.available2023-08-28T16:53:18Z
dc.date.created2023-05-22
dc.description.abstractenglishBackground: Patients with COVID-19 have a high incidence of acute kidney injury (AKI), which is associated with mortality. The objective of the study was to determine the factors associated with AKI in patients with COVID-19. Methodology: A retrospective cohort was established in two university hospitals in Bogotá, Colombia. Adults hospi‑ talized for more than 48 h from March 6, 2020, to March 31, 2021, with confrmed COVID-19 were included. The main outcome was to determine the factors associated with AKI in patients with COVID-19 and the secondary outcome was estimate the incidence of AKI during the 28 days following hospital admission. Results: A total of 1584 patients were included: 60.4% were men, 738 (46.5%) developed AKI, 23.6% were classifed as KDIGO 3, and 11.1% had renal replacement therapy. The risk factors for developing AKI during hospitalization were male sex (OR 2.28, 95% CI 1.73–2.99), age (OR 1.02, 95% CI 1.01–1.03), history of chronic kidney disease (CKD) (OR 3.61, 95% CI 2.03–6.42), High Blood Pressure (HBP) (OR 6.51, 95% CI 2.10–20.2), higher qSOFA score to the admission (OR 1.4, 95% CI 1.14–1.71), the use of vancomycin (OR 1.57, 95% CI 1.05–2.37), piperacillin/tazobactam (OR 1.67, 95% CI 1.2–2.31), and vasopressor support (CI 2.39, 95% CI 1.53–3.74). The gross hospital mortality for AKI was 45.5% versus 11.7% without AKI. Conclusions: This cohort showed that male sex, age, history of HBP and CKD, presentation with elevated qSOFA, in hospital use of nephrotoxic drugs and the requirement for vasopressor support were the main risk factors for devel‑ oping AKI in patients hospitalized for COVID-19.spa
dc.description.comunidadPacientes con COVID-19spa
dc.description.esciNospa
dc.description.indexingRevista Internacional - Indexadaspa
dc.description.orcidhttps://orcid.org/0000-0002-8892-9652spa
dc.description.orcidhttps://orcid.org/0000-0001-8845-9462spa
dc.description.orcidhttps://orcid.org/0000-0001-8213-4595spa
dc.description.orcidhttps://orcid.org/0000-0001-5902-2894spa
dc.description.orcidhttps://orcid.org/0000-0001-9852-749Xspa
dc.description.publindexA2spa
dc.description.quartilescopusQ2spa
dc.description.quartilewosQ3spa
dc.formatPDFspa
dc.format.mimetypeapplication/pdfspa
dc.identifierhttps://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-023-03172-8#citeasspa
dc.identifier.doihttps://doi.org/10.1186/s12882-023-03172-8spa
dc.identifier.instnameinstname:Pontificia Universidad Javerianaspa
dc.identifier.issn1471-2369spa
dc.identifier.reponamereponame:Repositorio Institucional - Pontificia Universidad Javerianaspa
dc.identifier.repourlrepourl:https://repository.javeriana.edu.cospa
dc.identifier.urihttp://hdl.handle.net/10554/65333
dc.language.isoengspa
dc.relation.citationendpage7spa
dc.relation.citationstartpage1spa
dc.relation.citationvolume24spa
dc.relation.ispartofjournalBMC Nephrologyspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.licenceAtribución-NoComercial 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subject.keywordAcute Kidney Injuryspa
dc.subject.keywordCOVID-19spa
dc.subject.keywordRisk factorsspa
dc.subject.keywordOutcomesspa
dc.titleRisk factors associated with acute kidney injury in a cohort of hospitalized patients with COVID-19spa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.type.hasversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.localArtículo de revistaspa

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