Efficacy of the use of perfluorocarbon as a temporary tamponade agent in severe ocular trauma and/or complex retinopexy: a scoping review

Pérez Pérez, Sara Margarita; Cárdenas Arias, Valentina; Jaramillo Ramírez, Daniela; Eduardo Martínez, Camilo; Tamayo Martínez, Nathalie

Efficacy of the use of perfluorocarbon as a temporary tamponade agent in severe ocular trauma and/or complex retinopexy: a scoping review

dc.contributor.author	Pérez Pérez, Sara Margarita
dc.contributor.author	Cárdenas Arias, Valentina
dc.contributor.author	Jaramillo Ramírez, Daniela
dc.contributor.author	Eduardo Martínez, Camilo
dc.contributor.author	Tamayo Martínez, Nathalie
dc.contributor.corporatename	Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Epidemiología Clínica y Bioestadística	spa
dc.date.accessioned	2024-02-26T16:57:55Z
dc.date.available	2024-02-26T16:57:55Z
dc.date.created	2024-01
dc.description.abstract	Background Perfluorocarbon (PFC)possesses unique chemical properties that favor the pigment epithelium’s adhesion and allows the drainage of subretinal fluid through retinal holes present in retinal detachment cases. However, PFC as a temporary tamponade agent has been limited due to its high potential for toxicity. Main body We conducted a scoping review regarding the use of PFC in vitreoretinal surgery as a temporary tamponade in subjects with severe ocular trauma or severe retinal detachment who received a therapeutic intervention (vitrectomy via posterior approach with the use of PFC as a temporary tamponade), compared to vitrectomy without the use of PFC as a temporary tamponade. Outcomes of interest were retinal reattachment, visual acuity (VA), postoperative complications and retinal toxicity. The search was performed in Medline, Medline In-Process & Other Non-Indexed Citations, Medline Daily Update, Embase databases. Reference lists from relevant review articles were also included. Two hundred thirty-eight studies were found, with no duplicate entries. In the first selection, 230 articles were eliminated; in the second selection, 6 additional articles were discarded. In total, 8 articles were obtained in this review. Two selected articles corresponded to animal studies and 6 to studies in humans. Regarding study design, 5 were case series, and 1 was a cohort study. Conclusion PFC as a short-term tamponade had high rates of reapplication, improved VA, and the most frequent adverse effects were reversible after PFC withdrawal. Nonetheless, the quality of the studies was poor. Studies with more rigorous methodologies are needed to determine visual and structural outcomes and potential risks of PFC use as a temporary tamponade in vitreoretinal surgery.	spa
dc.description.abstractenglish	Background Perfluorocarbon (PFC)possesses unique chemical properties that favor the pigment epithelium’s adhesion and allows the drainage of subretinal fluid through retinal holes present in retinal detachment cases. However, PFC as a temporary tamponade agent has been limited due to its high potential for toxicity. Main body We conducted a scoping review regarding the use of PFC in vitreoretinal surgery as a temporary tamponade in subjects with severe ocular trauma or severe retinal detachment who received a therapeutic intervention (vitrectomy via posterior approach with the use of PFC as a temporary tamponade), compared to vitrectomy without the use of PFC as a temporary tamponade. Outcomes of interest were retinal reattachment, visual acuity (VA), postoperative complications and retinal toxicity. The search was performed in Medline, Medline In-Process & Other Non-Indexed Citations, Medline Daily Update, Embase databases. Reference lists from relevant review articles were also included. Two hundred thirty-eight studies were found, with no duplicate entries. In the first selection, 230 articles were eliminated; in the second selection, 6 additional articles were discarded. In total, 8 articles were obtained in this review. Two selected articles corresponded to animal studies and 6 to studies in humans. Regarding study design, 5 were case series, and 1 was a cohort study. Conclusion PFC as a short-term tamponade had high rates of reapplication, improved VA, and the most frequent adverse effects were reversible after PFC withdrawal. Nonetheless, the quality of the studies was poor. Studies with more rigorous methodologies are needed to determine visual and structural outcomes and potential risks of PFC use as a temporary tamponade in vitreoretinal surgery	spa
dc.description.esci	Si	spa
dc.description.indexing	Revista Internacional - Indexada	spa
dc.description.quartilescopus	Q2	spa
dc.format	PDF	spa
dc.format.mimetype	application/pdf	spa
dc.identifier	https://journalretinavitreous.biomedcentral.com/articles/10.1186/s40942-023-00504-6	spa
dc.identifier.doi	https://doi.org/10.1186/s40942-023-00504-6	spa
dc.identifier.instname	instname:Pontificia Universidad Javeriana	spa
dc.identifier.issn	2056-9920	spa
dc.identifier.reponame	reponame:Repositorio Institucional - Pontificia Universidad Javeriana	spa
dc.identifier.repourl	repourl:https://repository.javeriana.edu.co	spa
dc.identifier.uri	http://hdl.handle.net/10554/66702
dc.language.iso	eng	spa
dc.relation.citationissue	6	spa
dc.relation.citationvolume	10	spa
dc.relation.ispartofjournal	International Journal of Retina and Vitreous	spa
dc.rights.coar	http://purl.org/coar/access_right/c_abf2	spa
dc.rights.licence	Atribución-NoComercial 4.0 Internacional	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc/4.0/	*
dc.subject	Perfluorocarbono	spa
dc.subject	Traumatismos oculares graves	spa
dc.subject.keyword	Perfluorocarbon	spa
dc.subject.keyword	Severe ocular trauma	spa
dc.title	Efficacy of the use of perfluorocarbon as a temporary tamponade agent in severe ocular trauma and/or complex retinopexy: a scoping review	spa
dc.type.coar	http://purl.org/coar/resource_type/c_beb9	spa
dc.type.hasversion	http://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.local	Artículo de revista	spa