Oral and oropharyngeal cancer in Colombia : an experience in a middle-income country cancer institute (2004-2013)
| dc.contributor.author | Pardo, Constanza | |
| dc.contributor.author | de Vries, Esther | |
| dc.contributor.corporatename | Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Epidemiología Clínica y Bioestadística | |
| dc.coverage.spatial | Colombia | spa |
| dc.coverage.temporal | 2004-2013 | |
| dc.date.accessioned | 2020-03-19T16:35:01Z | |
| dc.date.accessioned | 2020-04-15T13:27:04Z | |
| dc.date.available | 2020-03-19T16:35:01Z | |
| dc.date.available | 2020-04-15T13:27:04Z | |
| dc.date.created | 2018-02-22 | |
| dc.description.abstractenglish | Abstract Aims To provide demographical and clinical characteristics and estimations of 2-year overall survival (OS) of oral and oropharyngeal cancer (OOC) patients treated in the Colombian National Cancer Institute (INC) between 2004 and 2013. Methods All 1108 patients frst treated at INC for OOC in the three periods, without a prior cancer diagnosis, were included in this study. The INC hospital-based cancer registry was cross-linked with governmental databases to obtain follow-up information on all patients. Probability of surviving 24 months since the date of entry at INC was estimated using Kaplan–Meier methods, using the log-rank test to evaluate diferences between groups. In order to evaluate the relative efect of age, sex, clinical stage, anatomical site and type of health insurance on survival, we constructed a multivariate Cox proportional hazard model. Results The overall survival probability at 24 months was 48.2% (95% CI 45.3; 51.1), which was stable over time. Advanced age and clinical stage substantially afected overall survival, being 30.3% (95% CI 25.2; 35.4) for age > 70 and 34.7% (95% CI 29.4; 40.0) for stage IV disease. Hazard ratios were signifcantly higher for patients aged 70 and over [HR 1.99 (95% CI 1.41–2.79)] and advanced stage cancers [HR 2.16 (95% CI 1.55–3.01)], whereas patients with cancers of the tonsils or salivary glands had a strongly reduced risks compared to tongue and oral cavity cancer [HR 0.56 (95% CI 0.43–0.72)]. Conclusions Oral and oropharyngeal cancer has a very poor prognosis which was stable over time. Considering the late stage at diagnosis, much can be gained by improving early detection and treatment. | spa |
| dc.description.paginas | 19-26 | spa |
| dc.description.tipoarticulo | Artículo original | spa |
| dc.format | spa | |
| dc.format.mimetype | application/pdf | spa |
| dc.format.soporte | Papel / Electrónico | spa |
| dc.identifier | https://link.springer.com/article/10.1007/s41548-018-0005-0 | spa |
| dc.identifier.doi | https://doi.org/10.1007/s41548-018-0005-0 | spa |
| dc.identifier.issn | 2509-8837 (Electrónico) | spa |
| dc.identifier.uri | http://hdl.handle.net/10554/47741 | |
| dc.language | spa | spa |
| dc.rights.licence | Atribución-NoComercial 4.0 Internacional | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
| dc.source | Oral Cancer; Vol. 15 Núm. 2 (2018) | spa |
| dc.subject.keyword | Oral cancer | spa |
| dc.subject.keyword | Oropharyngeal cancer | spa |
| dc.subject.keyword | Survival | spa |
| dc.subject.keyword | Hospital-based cancer registry | spa |
| dc.subject.keyword | Colombia | spa |
| dc.title | Oral and oropharyngeal cancer in Colombia : an experience in a middle-income country cancer institute (2004-2013) | spa |
| dc.type | info:eu-repo/semantics/article | |
| dc.type.hasversion | http://purl.org/coar/version/c_ab4af688f83e57aa | |
| dc.type.local | Artículo de revista | spa |