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Report from the multinational irritable bowel syndrome initiative 2012

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dc.contributor.authorSharara, Ala
dc.contributor.authorMahachai, Varocha
dc.contributor.authorTalley, Nicholas J.
dc.contributor.authorQuigley, Eamonn M.M.
dc.contributor.authorPimentel, Mark
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Gastroenterología
dc.contributor.javerianateacherHani, Albis
dc.coverage.temporal2012
dc.date.accessioned2020-12-01T23:50:02Z
dc.date.available2020-12-01T23:50:02Z
dc.date.created2013-06-01
dc.description.abstractenglishIn 2012, a group of 29 internationally recognized experts in the pathophysiology, diagnosis, and treatment of irritable bowel syndrome (IBS) convened to audit the current state of IBS research. The meeting was preceded by a comprehensive online survey that focused on research needs for IBS diagnosis (particularly the strengths and shortcomings of current criteria), definitions used in clinical trials for IBS patients and “healthy controls,” potential biomarkers for IBS, and outcome measures in drug trials. While the purpose of the meeting was not to make binding recommendations, participants developed a framework for future questions and research needs in IBS. First, participants indicated the need for revised criteria for the diagnosis of IBS; in particular, inclusion of bloating and de-emphasis of pain as criteria were considered critical needs. Second, participants noted that definitions of normal, healthy controls varied widely among clinical trials; these definitions need to be standardized not only to improve the reliability of results, but also to better facilitate inter-trial comparisons and data synthesis. Third, participants highlighted the need for accurate biomarkers of disease. Fourth and finally, participants noted that further defining outcome measures, so that they are functionally relevant and reflect normalization of bowel function, is a critical need. Together, the discussions held at this workshop form a framework to address future research in IBS.spa
dc.description.indexingRevista Internacional - Indexadaspa
dc.description.orcidhttps://orcid.org/0000-0002-9219-4548spa
dc.description.quartilescopusQ1spa
dc.description.quartilewosQ1spa
dc.formatPDFspa
dc.format.mimetypeapplication/pdfspa
dc.identifierhttps://www.gastrojournal.org/article/S0016-5085(13)00700-2/abstractspa
dc.identifier.doihttps://doi.org/10.1053/j.gastro.2013.04.049spa
dc.identifier.instnameinstname:Pontificia Universidad Javerianaspa
dc.identifier.issn0016-5085 / 1528-0012 (Electrónico)spa
dc.identifier.reponamereponame:Repositorio Institucional - Pontificia Universidad Javerianaspa
dc.identifier.repourlrepourl:https://repository.javeriana.edu.cospa
dc.identifier.urihttp://hdl.handle.net/10554/51856
dc.language.isoengspa
dc.relation.citationendpageE5spa
dc.relation.citationissue7spa
dc.relation.citationstartpageE1spa
dc.relation.citationvolume144spa
dc.relation.ispartofjournalGastroenterologyspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.licenceAtribución-NoComercial 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.titleReport from the multinational irritable bowel syndrome initiative 2012spa
dc.type.coarhttp://purl.org/coar/resource_type/c_1843spa
dc.type.hasversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.localArtículo de revistaspa

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