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Testing the effects of long-acting steroids in edema and ecchymosis after closed rhinoplasty

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dc.contributor.authorGutiérrez Maldonado, Santiago
dc.contributor.authorWuesthoff, Carolina
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Departamento de Cirugía y Especialidades. Otorrinolaringología
dc.date.accessioned2020-08-28T01:20:22Z
dc.date.available2020-08-28T01:20:22Z
dc.date.created2014
dc.description.abstractenglishBackground: Steroids have proven to be of some benefit in rhinoplasty edema and ecchymosis when administered at a high and repeated dose. OBJECTIVE: To evaluate the effects of single-dose, long-acting intramuscular steroids on postoperative edema and ecchymosis after closed rhinoplasty with osteotomies compared with placebo. Methods: A randomized, double-blinded, placebo-controlled trial was performed. Fifty-four patients were randomly assigned to two groups: 28 received a single dose of long-acting dexamethasone (mean [± SD] dose 16±4 mg) immediately before anesthetic induction; the remaining 26 received an intramuscular injection of saline solution. The same surgeon performed all surgeries, with patients under general anesthesia. Acetaminophen was the only analgesic used to control postoperative pain. High-resolution digital photographs were taken on postoperative days 1, 3, 7 and 14. Scoring was performed separately for eyelid swelling and ecchymosis by an independent observer using a graded scale (0 to 5) for edema and a scoring system (0 to 13) for ecchymosis. Results: No statistically significant differences in terms of age, sex or amount of bleeding during surgery were found between the two groups. No statistically significant difference was observed in the decrease of both ecchymosis and edema between placebo and high-dose, long-acting dexamethasone. A statistically significant difference in operation time was found, favouring the steroid group. No severe complications were observed due to steroid use. Discussion: Osteotomies are basically a form of (controlled) trauma, with considerable disruption of the abundant blood vessels in this facial region and, therefore, are associated with with undesirable effects. A recent meta-analysis failed to show benefits of the use of steroids after postoperative day 3. Only a trend toward reduction in edema and ecchymosis with the use of long-acting steroids compared with placebo was demonstrated in the present study. Conclusion: There was no benefit in administering single-dose, longacting steroids in patients undergoing closed rhinoplasty with osteotomies.spa
dc.description.paginas83-87spa
dc.description.quartilescopusQ3spa
dc.description.quartilewosQ4spa
dc.description.tipoarticuloArtículo originalspa
dc.formatPDFspa
dc.format.mimetypeapplication/pdfspa
dc.format.soportePapel / Electrónicospa
dc.identifierhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116320/spa
dc.identifier.issn2292-5503 / 2292-5511 (Electrónico)spa
dc.identifier.urihttp://hdl.handle.net/10554/50874
dc.languageInglésspa
dc.rights.licenceAtribución-NoComercial 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.sourcePlastic Surgery; Vol. 22 Núm. 2 (2014)spa
dc.subject.keywordEdemaspa
dc.subject.keywordEcchymosisspa
dc.subject.keywordRhinoplastyspa
dc.subject.keywordSteroidsspa
dc.titleTesting the effects of long-acting steroids in edema and ecchymosis after closed rhinoplastyspa
dc.typeinfo:eu-repo/semantics/article
dc.type.hasversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.localArtículo de revistaspa

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