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Hippocampal subfields and decline in activities of daily living in Alzheimer’s disease and dementia with Lewy bodies

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dc.contributor.authorBorda, Miguel Germán
dc.contributor.authorJaramillo-Jimenez, Alberto
dc.contributor.authorTovar-Rios, Diego A
dc.contributor.authorFerreira, Daniel
dc.contributor.authorGarcia-Cifuentes, Elkin
dc.contributor.authorVik-Mo, Audun Osland
dc.contributor.authorAarsland, Vera
dc.contributor.authorAarsland, Dag
dc.contributor.authorOppedal, Ketil
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimiento
dc.date.accessioned2021-04-21T23:30:20Z
dc.date.available2021-04-21T23:30:20Z
dc.date.created2020-09-24
dc.description.abstractenglishBackground: Hippocampal atrophy is presented in Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB). Cognition, dual-tasks, muscular function, goal-related behaviors and neuropsychiatric symptoms are linked to hippocampal volumes and may lead to functional decline in activities of daily living. We examined the association between baseline hippocampal subfield volumes (HSv) in mild AD and DLB, and functional decline. Materials & methods: 12 HSv were computed from structural magnetic resonance images using Freesurfer 6.0 segmentation. Functional decline was assessed using the rapid disability rating scale score. Linear regressions were conducted. Results: In AD, HSv were smaller bilaterally. However, HSv were not associated with functional decline. Conclusion: Functional decline does not depend on HSv in mild AD and DLB.spa
dc.description.indexingRevista Internacional - Indexadaspa
dc.description.quartilescopusQ3spa
dc.formatPDFspa
dc.format.mimetypeapplication/pdfspa
dc.identifierhttps://www.futuremedicine.com/doi/pdf/10.2217/nmt-2020-0039spa
dc.identifier.doihttps://doi.org/10.2217/nmt-2020-0039spa
dc.identifier.instnameinstname:Pontificia Universidad Javerianaspa
dc.identifier.issn1758-2024 / 1758-2032 (Electrónico)spa
dc.identifier.reponamereponame:Repositorio Institucional - Pontificia Universidad Javerianaspa
dc.identifier.repourlrepourl:https://repository.javeriana.edu.cospa
dc.identifier.urihttp://hdl.handle.net/10554/53659
dc.language.isoengspa
dc.relation.citationendpage367spa
dc.relation.citationissue6spa
dc.relation.citationstartpage357spa
dc.relation.citationvolume10spa
dc.relation.ispartofjournalNeurodegenerative Disease Managementspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.licenceAtribución-NoComercial 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subject.keywordActivities of daily livingspa
dc.subject.keywordAlzheimer’s diseasespa
dc.subject.keywordDementia with Lewy bodiesspa
dc.subject.keywordFunctional declinespa
dc.subject.keywordHippocampal subfieldsspa
dc.titleHippocampal subfields and decline in activities of daily living in Alzheimer’s disease and dementia with Lewy bodiesspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.hasversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.localArtículo de revistaspa

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