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Effects of performing morning versus afternoon exercise on glycemic control and hypoglycemia frequency in type 1 diabetes patients on sensor-augmented insulin pump therapy

dc.contributor.authorGómez Medina, Ana María
dc.contributor.authorGómez, Claudia
dc.contributor.authorAschner Montoya, Pablo
dc.contributor.authorVeloza, Angélica
dc.contributor.authorMuñoz, Oscar
dc.contributor.authorRubio, Claudia
dc.contributor.authorVallejo, Santiago
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Enfermedades Crónicas del Adulto
dc.contributor.corporatenamePontificia Universidad Javeriana. Facultad de Medicina. Departamento de Endocrinología
dc.date.accessioned2020-04-14T17:25:19Z
dc.date.accessioned2020-05-08T15:23:23Z
dc.date.available2020-04-14T17:25:19Z
dc.date.available2020-05-08T15:23:23Z
dc.date.created2015-01-01
dc.description.abstractenglishBackground: Although physical exercise (PE) is recommended for individuals with type 1 diabetes (DM1), participation in exercise is challenging because it increases the risk of severe hypoglycemia and the available therapeutic options to prevent it frequently result in hyperglycemia. There is no clear recommendation about the best timing for exercise. The aim of this study was to compare the risk of hypoglycemia after morning or afternoon exercise sessions up to 36 hours postworkout. Methods: This randomized crossover study enrolled subjects with DM1, older than 18 years of age, on sensor-augmented insulin pump (SAP) therapy. Participants underwent 2 moderate-intensity exercise sessions; 1 in the morning and 1 in the afternoon, separated by a 7 to 14 day wash-out period. Continuous glucose monitoring (CGM) data were collected 24 hours before, during and 36 hours after each session. Results: Thirty-five subjects (mean age 30.31 ± 12.66 years) participated in the study. The rate of hypoglycemia was significantly lower following morning versus afternoon exercise sessions (5.6 vs 10.7 events per patient, incidence rate ratio, 0.52; 95% CI, 0.43-0.63; P < .0001). Most hypoglycemic events occurred 15-24 hours after the session. On days following morning exercise sessions, there were 20% more CGM readings in near-euglycemic range (70-200 mg/dL) than on days prior to morning exercise (P = .003). Conclusions: Morning exercise confers a lower risk of late-onset hypoglycemia than afternoon exercise and improves metabolic control on the subsequent day.spa
dc.description.paginas619-624spa
dc.description.quartilescopusQ1spa
dc.description.tipoarticuloArtículo originalspa
dc.formatPDFspa
dc.format.mimetypeapplication/pdfspa
dc.format.soportePapel / Electrónicospa
dc.identifierhttps://journals.sagepub.com/doi/10.1177/1932296814566233spa
dc.identifier.doihttps://doi.org/10.1177/1932296814566233spa
dc.identifier.issn1932-2968 / 1932-2968 (Electrónico)spa
dc.identifier.urihttp://hdl.handle.net/10554/48184
dc.languagespaspa
dc.rights.licenceAtribución-NoComercial 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.sourceJournal of Diabetes Science and Technology; Vol. 9 Núm. 3 (2015)spa
dc.subject.keywordDiabetes mellitus type 1spa
dc.subject.keywordExercisespa
dc.subject.keywordHypoglycemiaspa
dc.subject.keywordInsulin infusion systemspa
dc.titleEffects of performing morning versus afternoon exercise on glycemic control and hypoglycemia frequency in type 1 diabetes patients on sensor-augmented insulin pump therapyspa
dc.typeinfo:eu-repo/semantics/article
dc.type.hasversionhttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.localArtículo de revistaspa

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