Associated factors for mortality in a COVID-19 colombian cohort : is the third wave relevant when Mu variant was predominant epidemiologically?
dc.contributor.author | Álvarez Moreno, Carlos | |
dc.contributor.author | Valderrama-Beltrán, Sandra Liliana | |
dc.contributor.author | Silva, Ronaldo | |
dc.contributor.author | De La Hoz Siegler, Ilich Herbert | |
dc.contributor.author | Varón Vega, Fabio Andrés | |
dc.contributor.author | Martínez Vernaza, Samuel | |
dc.contributor.author | Ordoñez Blanco, Ivonne Tatiana | |
dc.contributor.author | Padilla, Mónica | |
dc.contributor.author | Mesa Rubio, María Lucía | |
dc.contributor.author | Castañeda Pascagaza, Laura Carmenza | |
dc.contributor.author | Rojas, José Antonio | |
dc.contributor.author | Bravo Ojeda, Juan Sebastián | |
dc.contributor.author | Villa, Jaime | |
dc.contributor.author | Chacón Sarmiento, Julio Alberto | |
dc.contributor.author | Yomayusa, Nancy | |
dc.contributor.author | Patiño, Sandra | |
dc.contributor.author | Gómez-Nieto, Katherine | |
dc.contributor.author | Martínez Pinzón, Viviana Lorena | |
dc.contributor.author | Ramírez Cogollo, Angélica María | |
dc.contributor.author | Toloza, Carlos | |
dc.contributor.author | Diaz Puentes, Melissa | |
dc.contributor.author | Canas, Alejandra | |
dc.contributor.author | Manrique Andrade, Maria Margarita | |
dc.contributor.author | Tarud Ayub, Roberto | |
dc.contributor.author | López Mora, María José | |
dc.contributor.author | Pachón Espinosa, María Julieta | |
dc.contributor.author | Cortés, Jorge Alberto | |
dc.contributor.author | Sánchez, Laura Catalina | |
dc.contributor.author | Chacón Acevedo, Kelly Rocío | |
dc.contributor.author | Rengifo, Paola | |
dc.contributor.author | Tambini, Ginna | |
dc.contributor.author | Bertagnolio, Silvia | |
dc.contributor.author | Diaz, Janet | |
dc.contributor.author | Thwin, Soe-Soe | |
dc.contributor.author | Reveiz, Ludovic | |
dc.contributor.corporatename | Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Neumología | spa |
dc.contributor.corporatename | Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Infectología | |
dc.contributor.corporatename | Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Pediatría | |
dc.contributor.corporatename | Pontificia Universidad Javeriana. Facultad de Medicina. Departamento de Medicina Interna. Medicina Interna | |
dc.contributor.javerianateacher | Valderrama-Beltrán, Sandra Liliana | |
dc.contributor.javerianateacher | Canas, Alejandra | |
dc.coverage.city | Barranquilla (Colombia) | spa |
dc.coverage.city | Bogotá (Colombia) | spa |
dc.coverage.city | Cali (Colombia) | spa |
dc.coverage.spatial | Colombia | spa |
dc.coverage.temporal | 2020-2021 | spa |
dc.date.accessioned | 2023-09-07T14:16:32Z | |
dc.date.available | 2023-09-07T14:16:32Z | |
dc.date.created | 2023-05-09 | |
dc.description.abstractenglish | Objectives: To evaluate the association between Colombia's third wave when the Mu variant was predominant epidemiologically (until 75%) in Colombia and COVID-19 all-cause in-hospital mortality. Methods: In this retrospective cohort, we included hospitalized patients ≥18 years with SARS-CoV-2 infection between March 2020 to September 2021 in ten hospitals from three cities in Colombia. Description analysis, survival, and multivariate Cox regression analyses were performed to evaluate the association between the third epidemic wave and in-hospital mortality. Results: A total of 25,371 patients were included. The age-stratified time-to-mortality curves showed differences according to epidemic waves in patients ≥75 years (log-rank test p = 0.012). In the multivariate Cox analysis, the third wave was not associated with increased mortality relative to the first wave (aHR 0.95; 95%CI 0.84–1.08), but there was an interaction between age ≥75 years and the third wave finding a lower HR for mortality (aHR 0.56, 95%CI 0.36–0.86). Conclusions: We did not find an increase in in-hospital mortality during the third epidemic wave in which the Mu variant was predominant in Colombia. The reduced hazard in mortality in patients ≥75 years hospitalized in the third wave could be explained by the high coverage of SARS-CoV-2 vaccination in this population and patients with underlying conditions. | spa |
dc.description.comunidad | Pacientes con COVID-19 | spa |
dc.description.esci | No | spa |
dc.description.indexing | Revista Internacional - Indexada | spa |
dc.description.orcid | https://orcid.org/0000-0003-1833-1599 | spa |
dc.description.orcid | https://orcid.org/0000-0001-5363-5729 | spa |
dc.description.orcid | https://orcid.org/0000-0001-6964-2229 | spa |
dc.description.orcid | https://orcid.org/0000-0003-3975-2835 | spa |
dc.description.orcid | https://orcid.org/0000-0001-9441-4375 | spa |
dc.description.publindex | A1 | spa |
dc.description.quartilescopus | Q1 | spa |
dc.description.quartilewos | Q1 | spa |
dc.format | spa | |
dc.format.mimetype | application/pdf | spa |
dc.identifier | https://www.sciencedirect.com/science/article/pii/S147789392300039X | spa |
dc.identifier.doi | https://doi.org/10.1016/j.tmaid.2023.102579 | spa |
dc.identifier.instname | instname:Pontificia Universidad Javeriana | spa |
dc.identifier.issn | 1477-8939 / 1873-0442 (Electrónico) | spa |
dc.identifier.reponame | reponame:Repositorio Institucional - Pontificia Universidad Javeriana | spa |
dc.identifier.repourl | repourl:https://repository.javeriana.edu.co | spa |
dc.identifier.uri | http://hdl.handle.net/10554/65393 | |
dc.language.iso | eng | spa |
dc.relation.citationendpage | 9 | spa |
dc.relation.citationstartpage | 1 | spa |
dc.relation.citationvolume | 53 | spa |
dc.relation.ispartofjournal | Travel Medicine and Infectious Disease | spa |
dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | spa |
dc.rights.licence | Atribución-NoComercial 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | * |
dc.subject.keyword | COVID-19 | spa |
dc.subject.keyword | Variant Mu | spa |
dc.subject.keyword | Epidemic wave | spa |
dc.subject.keyword | Risk factors | spa |
dc.title | Associated factors for mortality in a COVID-19 colombian cohort : is the third wave relevant when Mu variant was predominant epidemiologically? | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | spa |
dc.type.hasversion | http://purl.org/coar/version/c_ab4af688f83e57aa | |
dc.type.local | Artículo de revista | spa |
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